- Source: 4-Hydroxy-3-methoxyamphetamine
3/info/4" target="_blank">4-3/info/hydroxy" target="_blank">Hydroxy-3-methoxyamphetamine (HMA), also known as 3-O-methyl-α-methyldopamine, is an active metabolite of 3,3/info/4" target="_blank">4-methylenedioxymethamphetamine (MDMA). It is substantially less potent than MDMA or 3,3/info/4" target="_blank">4-methylenedioxyamphetamine (MDA) as a monoamine releasing agent in vitro. Nonetheless, HMA has been found to induce the release of serotonin, norepinephrine, and dopamine with EC50Tooltip half-maximal effective concentration values of 897 nM, 694 nM, and 1450–3423 nM, respectively, and hence acts as a lower-potency serotonin–norepinephrine–dopamine releasing agent (SNDRA). The predicted log P of HMA is 0.6.
See also
3/info/4" target="_blank">4-3/info/hydroxy" target="_blank">Hydroxy-3-methoxymethamphetamine (HMMA)
3,3/info/4" target="_blank">4-Dihydroxymethamphetamine (HHMA)
3,3/info/4" target="_blank">4-Dihydroxyamphetamine (HMA; α-methyldopamine)
References
Kata Kunci Pencarian:
- 4-Hydroxy-3-methoxyamphetamine
- 4-Hydroxy-3-methoxymethamphetamine
- Para-Methoxyamphetamine
- MDMA
- C10H15NO2
- Monoamine releasing agent
- Controlled Drugs and Substances Act
- 4-Methylthioamphetamine
- Substituted amphetamine
- List of psychedelic drugs
