• Source: Adipokine

The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos, movement) are cytokines (cell signaling proteins) secreted by adipose tissue. Some contribute to an obesity-related low-grade state of inflammation or to the development of metabolic syndrome, a constellation of diseases including, but not limited to, type 2 diabetes, cardiovascular disease and atherosclerosis. The first adipokine to be discovered was leptin in 1994. Since that time, hundreds of adipokines have been discovered.
Members include:

Leptin
Adiponectin
Apelin
chemerin
interleukin-6 (IL-6)
monocyte chemotactic protein-1 (MCP-1)
plasminogen activator inhibitor-1 (PAI-1)
retinol binding protein 4 (RBP4)
tumor necrosis factor
visfatin
omentin
vaspin (SERPINA12)
progranulin
CTRP-4
Interleukin 8 (IL-8), interleukin 10 (IL-10), interferon gamma (IFN-γ) and inducible protein 10 (IP-10 or CXCL10) have been shown to be associated with excessive body weight.




See also


Adipose tissue
Hepatokines
Myokines




Notes






External links


Adipokines at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• Tiazolidindion
• Adipokine
• Chemerin
• Adiponectin
• FAM132A
• Gastric inhibitory polypeptide
• Tirzepatide
• Thiazolidinedione
• Diabetes
• CMKLR1
• Obesity