- Source: Androgen ester
An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone). Esterification renders AAS into metabolism-resistant prohormones of themselves, improving oral bioavailability, increasing lipophilicity, and extending the elimination half-life (which necessitates less frequent administration). In addition, with intramuscular injection, AAS esters are absorbed more slowly into the body, further improving the elimination half-life. Aside from differences in pharmacokinetics (e.g., duration), these esters essentially have the same effects as the parent drugs. They are used in androgen replacement therapy (ART), among other indications. Examples of androgen esters include testosterone esters such as testosterone cypionate, testosterone enanthate, testosterone propionate, and testosterone undecanoate and nandrolone esters such as nandrolone decanoate and nandrolone phenylpropionate.
See also
List of androgen esters
List of androgens/anabolic steroids
Steroid ester
Estrogen ester
Progestogen ester
References
Further reading
Vermeulen A (1975). "Longacting steroid preparations". Acta Clin Belg. 30 (1): 48–55. doi:10.1080/17843286.1975.11716973. PMID 1231448.
Kata Kunci Pencarian:
- Testosteron enantat
- Testosteron sipionat
- Testosteron undekanoat
- Metilparaben
- Steroid anabolik
- Kulit
- Kortikosteroid
- Estradiol
- Siproteron asetat
- Lipida
- Androgen ester
- List of androgen esters
- Metenolone enanthate
- Drostanolone propionate
- Trestolone enanthate
- Boldenone undecylenate
- Trenbolone acetate
- Metenolone acetate
- Trenbolone hexahydrobenzylcarbonate
- Androgen replacement therapy