- Source: D-sorbitol dehydrogenase (acceptor)
In enzymology, a D-sorbitol dehydrogenase (acceptor) (EC 1.1.99.21) is an enzyme that catalyzes the chemical reaction
D-sorbitol + acceptor
⇌
{\displaystyle \rightleftharpoons }
L-sorbose + reduced acceptor
Thus, the two substrates of this enzyme are D-sorbitol and acceptor, whereas its two products are L-sorbose and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-sorbitol:acceptor 1-oxidoreductase. This enzyme is also called D-sorbitol:(acceptor) 1-oxidoreductase. This enzyme participates in fructose and mannose metabolism. It employs one cofactor, FAD.
References
Shinagawa E, Ameyama M (1982). "Purification and characterization of D-sorbitol dehydrogenase from membrane of Gluconobacter suboxydans var-alpha". Agric. Biol. Chem. 46: 135–141. doi:10.1271/bbb1961.46.135.
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