- Source: Deoxyadenosine
Deoxyadenosine (symbol dA or dAdo) is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2′ position of its ribose sugar moiety. Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA.
In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).
See also
Deoxyribonucleotide
Cordycepin (3′-deoxyadenosine)
Severe combined immunodeficiency
References
Kata Kunci Pencarian:
- Malondialdehid
- Deoxyadenosine
- Deoxyadenosine monophosphate
- Deoxyadenosine triphosphate
- Cordycepin
- Deoxyadenosine diphosphate
- 5'-deoxyadenosine deaminase
- Islatravir
- Deoxyadenosine kinase
- Adenine
- Nucleotide
