• Source: Fixed drug reaction

Fixed drug reactions are common and so named because they recur at the same site with each exposure to a particular medication. Medications inducing fixed drug eruptions are usually those taken intermittently.




Signs and symptoms


A painful and itchy reddish/purple patch of skin that occurs in the same location with repeated exposures to the causative drug is the classic presentation of a fixed drug reaction. The lips, genitals, and hands are often involved.




Cause


Medications that are commonly implicated as a cause of fixed drug eruptions include the following:

Cetirizine
Ciprofloxacin
Clarithromycin
Cotrimoxazole
Doxycycline
Fluconazole
NSAIDs (e.g., ibuprofen, etoricoxib, naproxen)
Phenytoin
Pseudoephedrine
Trimethoprim




See also


Drug eruption
List of cutaneous conditions
List of human leukocyte antigen alleles associated with cutaneous conditions
Stevens–Johnson syndrome




References






External links

Kata Kunci Pencarian:

• Kalium permanganat
• Natrium
• Fixed drug reaction
• Combination drug
• Drug eruption
• Cradle cap
• Prurigo
• Autoimmune progesterone dermatitis
• Generalized bullous fixed drug eruption
• List of skin conditions
• Nonsteroidal anti-inflammatory drug
• Tonic water