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    • Source: Sure

      • Sure may refer to:

      Seemingly unrelated regressions
      Series of Unsurprising Results in Economics (SURE), an economics academic journal
      Sure, as probability, see certainty
      Sure (brand), a brand of antiperspirant deodorant
      Sure (company), a telecommunications company operating in British Crown Dependencies and Overseas Territories
      Stein's unbiased risk estimate (SURE), in estimation theory
      The river Sauer


      In music


      "Sure" (Every Little Thing song), from the album Eternity
      "Sure" (Take That song), from the album Nobody Else


      See also


      Shure

    • Source: SurE

      • In molecular biology, the protein domain surE refers to survival protein E. It was originally found that cells that did not contain this protein, could not survive in the stationary phase, at above normal temperatures, and in high-salt media. Hence the name, survival protein E. It is a metal ion-dependent phosphatase that is found in bacteria, and eukaryotes. It is an important stress response protein. This domain is found in acid phosphatases (EC), 5'-nucleotidases (EC), 3'-nucleotidases (EC) and exopolyphosphatases (EC).


      Interaction with pcm gene


      The gene, surE, is part of a bicistronic operon found upstream of the pcm gene. When mutated, their phenotypes, or physical characteristics, are very similar and indicate that both gene products are important for survival under stressful conditions.


      Function


      The C-terminal domain is important mainly for maintaining the oligomeric state of the protein, SurE. The N-terminal domain is thought to be part of the functional domain. Since the SurE is a phosphatase enzyme it removes a phosphate group from a substance, affecting that substance's role in signal transduction.


      Structure


      This protein consists of two protein domain. One is a large, globular N-terminal
      domain and the other is a smaller C-terminal domain.


      = N-terminal domain

      =
      The N-terminal domain contains a three-layer alpha/beta/alpha sandwich that is homologous with the Rossmann fold (CATH class 3.40.50.170) of which the major feature is a long beta sheet that is composed of nine mostly parallel beta strands. SurEstructural domain has a similar topology to the N-terminal protein domain of the glutaminase/asparaginase family.


      = C-terminal domain

      =
      The C-terminal domain, has 3 beta strands and two protrusions; one of which is a C-terminal alpha helix, and the second is a beta hairpin.


      References

    • Source: SuRe

      • SuRe (The Standard for Sustainable and Resilient Infrastructure) is a global voluntary standard which integrates key criteria of sustainability and resilience into infrastructure development and upgrade. It has been developed by the Swiss Global Infrastructure Basel Foundation and the French bank Natixis.
      The aim of the standard is twofold: it not only guides project owners to develop infrastructure projects that perform highly with regard to sustainability and resilience aspects — taking into account social, environmental and governance criteria and best practices; it also serves as a tool to communicate the sustainability and resilience benefits to potential investors, thus channelling more financial flows into infrastructure development and boosting sustainable socioeconomic development globally.
      The Standard was launched at 2015 United Nations Climate Change Conference (COP21).
      SuRe® is governed by three bodies (Secretariat, Standard Committee and Stakeholder Council) in an effort to maintain a balanced representation of stakeholders in the standard development and provide transparent and due process safeguards while ensuring independence, transparency and credibility.
      GIB has also developed the SuRe® SmartScan, a simplified version of the SuRe® Standard which serves as a self-assessment tool for infrastructure project developers. It provides them with a comprehensive and time-efficient analysis of the various themes covered by the SuRe® Standard, offering a solid foundation for projects that are planning to become certified by the SuRe® Standard in the future. Upon completion of the SmartScan, project developers receive a spider diagram evaluation, which indicates their project’s performance in the different themes and benchmarks the performances with other SmartScan assessed projects.


      References

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