• Source: Triazolobenzodiazepine

Triazolobenzodiazepines (TBZD) are a class of benzodiazepine (BZD) derivative pharmaceutical drugs. Chemically, they differ from other benzodiazepines by having an additional triazole ring fused to the diazepine ring. The triazole and diazepine rings share a nitrogen atom.
Examples include:

Adinazolam
Alprazolam
Bromazolam
Clonazolam
Estazolam
Flualprazolam
Flubromazolam
Flunitrazolam
Nitrazolam
Pyrazolam
Triazolam
Zapizolam




Synthesis


Synthesis of 1-methyltriazolobenzodiazepines (alprazolam type) is possible by heating 1,4-benzodiazepin-2-thiones with hydrazine and acetic acid in n-butanol under reflux.




References






External links


Media related to Triazolobenzodiazepines at Wikimedia Commons

Kata Kunci Pencarian:

• Triazolobenzodiazepine
• Estazolam
• Bromazolam
• Triazolam
• Alprazolam
• Flunitrazolam
• Clonazolam
• Nitrazolam
• Pynazolam
• Whitney Houston