- Source: U7 small nuclear RNA
The U7 small nuclear RNA (U7 snRNA) is an RNA molecule and a component of the small nuclear ribonucleoprotein complex (U7 snRNP). The U7 snRNA is required for histone pre-mRNA processing.
The 5' end of the U7 snRNA binds the HDE (histone downstream element), a conserved purine-rich region, located 15 nucleotides downstream the histone mRNA cleavage site. The binding of the HDE region by the U7 snRNA, through complementary base-pairing, is an important step for the future recruitment of cleavage factors during histone pre-mRNA processing.
See also
Duchenne muscular dystrophy
Histone 3' UTR stem-loop
LSM10
References
Further reading
External links
Page for U7 small nuclear RNA at Rfam
The uRNA database
Kata Kunci Pencarian:
- U7 small nuclear RNA
- Small nuclear RNA
- U7
- SnRNP
- LSM10
- Post-transcriptional modification
- LSm
- SNRPB
- Small Cajal body specific RNA 14
- Small nuclear ribonucleoprotein polypeptide F