- Source: (hydroxymethylglutaryl-CoA reductase (NADPH))-phosphatase
The enzyme [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase (EC 3.1.3.47) catalyzes the reaction
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O
⇌
{\displaystyle \rightleftharpoons }
[hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphate phosphohydrolase. This enzyme is also called reductase phosphatase.
References
Gil G, Hegardt FG (1982). "Some properties of purified 3-hydroxy-3-methylglutaryl coenzyme A reductase phosphatases from rat liver". Arch. Biochem. Biophys. 214 (1): 192–8. doi:10.1016/0003-9861(82)90022-4. PMID 6282220.
Gil G, Sitges M, Hegardt FG (1981). "Purification and properties of rat liver hydroxymethylglutaryl coenzyme A reductase phosphatases". Biochim. Biophys. Acta. 663 (1): 211–21. doi:10.1016/0005-2760(81)90207-1. PMID 6260210.
Kata Kunci Pencarian:
- HMG-CoA reductase
- (hydroxymethylglutaryl-CoA reductase (NADPH))-phosphatase
- AMP-activated protein kinase
- List of EC numbers (EC 3)
- List of MeSH codes (D08)
- List of EC numbers (EC 2)
