- Source: (S)-coclaurine-N-methyltransferase
In enzymology, a (S)-coclaurine-N-methyltransferase (EC 2.1.1.140) is an enzyme that catalyzes the chemical reaction
S-adenosyl-L-methionine + (S)-coclaurine
⇌
{\displaystyle \rightleftharpoons }
S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine
Thus, the two substrates of this enzyme are S-adenosyl methionine and (S)-coclaurine, whereas its two products are S-adenosylhomocysteine and (S)-N-methylcoclaurine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase. This enzyme participates in alkaloid biosynthesis.
References
Loeffler S, Deus-Neumann B, Zenk MH (1995). "S-Adenosyl-L-methionine: (S)-coclaurine-N-methyltransferase from Tinospora cordifolia". Phytochemistry. 38 (6): 1387–1395. doi:10.1016/0031-9422(94)00813-9.