- Source: (S)-N-acetyl-1-phenylethylamine hydrolase
In enzymology, a (S)-N-acetyl-1-phenylethylamine hydrolase (EC 3.5.1.85) is an enzyme that catalyzes the chemical reaction
N-acetylphenylethylamine + H2O
⇌
{\displaystyle \rightleftharpoons }
phenethylamine + acetate
Thus, the two substrates of this enzyme are N-acetylphenylethylamine and H2O, whereas its two products are phenethylamine and acetate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is (S)-N-acetylphenylethylamine:H2O hydrolase. At least one compound, phenylmethanesulfonylfluoride is known to inhibit this enzyme.
References
Brunella A, Graf M, Kittelmann M, Lauma K, Ghisalba O (1997). "Production, purification, and characterization of a highly enantioselective (S)-N-acetyl-1-phenylethyl amidohydrolase from Rhodococcus". Appl. Microbiol. Biotechnol. 47 (5): 515–520. doi:10.1007/s002530050965.
