• Source: 1,2-Butanediol

1,2-Butanediol is the organic compound with the formula HOCH2(HO)CHCH2CH3. It is classified as a vic-diol (glycol). It is chiral, although typically it is encountered as the racemic mixture. It is a colorless liquid.




Preparation


This diol was first described by Charles-Adolphe Wurtz in 1859.
It is produced industrially by hydration of 1,2-epoxybutane.

This process requires a ten- to twenty-fold excess of water to suppress the formation of polyethers. Depending on the amount of excess water, the selectivity varies from 70 to 92%. Sulfuric acid or strongly acidic ion exchange resins may be used as catalysts, which allows the reaction to occur under 160 °C and at slightly above atmospheric pressure.
1,2-Butanediol is a byproduct of the production of 1,4-butanediol from butadiene. It is also a byproduct of the catalytic hydrocracking of starches and sugars such as sorbitol to ethylene glycol and propylene glycol.
It can also be obtained from the dihydroxylation of but-1-ene by OsO4.




Applications


It has been patented for the production of polyester resins and plasticizers. It is a potential feedstock for the industrial production of α-ketobutyric acid, a precursor to some amino acids.




Safety


The LD50 (rats, oral) is 16g/kg.




Notes






References






External links


International Chemical Safety Card 03
SIDS Initial Assessment Report for 1,2-Butanediol from the Organisation for Economic Co-operation and Development (OECD)

Kata Kunci Pencarian:

• 1,2-Butanediol
• Butanediol
• 1,4-Butanediol
• 1,3-Butanediol
• C4H10O2
• Ethylene glycol
• Β-Hydroxybutyric acid
• 1,4-Butanediol diglycidyl ether
• List of water-miscible solvents
• 1,4-Dichlorobutane