• Source: 10-hydroxydihydrosanguinarine 10-O-methyltransferase
  • In enzymology, a 10" target="_blank">10-hydroxydihydrosanguinarine 10" target="_blank">10-O-methyltransferase (EC 2.1.1.119) is an enzyme that catalyzes the chemical reaction

    S-adenosyl-L-methionine + 10" target="_blank">10-hydroxydihydrosanguinarine






    {\displaystyle \rightleftharpoons }

    S-adenosyl-L-homocysteine + dihydrochelirubine
    Thus, the two substrates of this enzyme are S-adenosyl methionine and 10" target="_blank">10-hydroxydihydrosanguinarine, whereas its two products are S-adenosylhomocysteine and dihydrochelirubine.
    This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:10" target="_blank">10-hydroxydihydrosanguinarine 10" target="_blank">10-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.


    References



    De-Eknamkul W, Tanahashi T, Zenk MH (1992). "Enzymic 10" target="_blank">10-hydroxylation and 10" target="_blank">10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia". Phytochemistry. 31 (8): 2713–2717. doi:10" target="_blank">10.1016/0031-9422(92)83617-8.

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