- Source: 11-cis-retinyl-palmitate hydrolase
The enzyme 11-cis-retinyl-palmitate hydrolase (EC 3.1.1.63) catalyzes the reaction
11-cis-retinyl palmitate + H2O
⇌
{\displaystyle \rightleftharpoons }
11-cis-retinol + palmitate
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 11-cis-retinyl-palmitate acylhydrolase. Other names in common use include 11-cis-retinol palmitate esterase, and RPH. This enzyme participates in retinol metabolism. This enzyme has at least one effector, Bile salt.
References
Blaner WS, Das SR, Gouras P, Flood MT (1987). "Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates of human retinal epithelial cells". J. Biol. Chem. 262 (1): 53–8. PMID 3793734.
Blaner WS, Prystowsky JH, Smith JE, Goodman DS (1984). "Rat liver retinyl palmitate hydrolase activity. Relationship to cholesteryl oleate and triolein hydrolase activities". Biochim. Biophys. Acta. 794 (3): 419–27. doi:10.1016/0005-2760(84)90008-0. PMID 6743673.