- Source: 1980 Clemson Tigers baseball team
The 1980 Clemson Tigers baseball team represented Clemson University in the 1980 NCAA Division I baseball season. The team played their home games at Beautiful Tiger Field in Clemson, South Carolina.
The team was coached by Bill Wilhelm, who completed his twenty-third season at Clemson. The Tigers reached the 1980 College World Series, their fifth appearance in Omaha.