• Source: 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase

2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (EC 1.1.1.312, 2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase, 4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP+ oxidoreductase, alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase, 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase, LigC, ProD) is an enzyme with systematic name 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal:NADP+ 2-oxidoreductase. This enzyme catalyses the following chemical reaction

4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP+



⇌


{\displaystyle \rightleftharpoons }

2-oxo-2H-pyran-4,6-dicarboxylate + NADPH + H+
Unsubstituted aliphatic or aromatic aldehydes or glucose cannot serve as substrate of this enzyme.




References






External links


2-hydroxy-4-carboxymuconate+semialdehyde+hemiacetal+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
• LIGC
• List of EC numbers (EC 1)