- Source: 2-MCPD
2-MCPD (2-chloropropane-1,3-diol) is an organic chemical compound with the formula ClCH(CH2(OH))2. It is a colorless liquid. The compound has attracted notoreity as a food contaminant. Together with the 3-MCPD, it is one of two chloropropanols food contaminants. It is suspected to be carcinogenic in humans.
2-MCPD, together with its isomer 3-MCPD, is thought to be produced when fat-containing foods are treated at high temperatures with hydrochloric acid. Such treatments are sometimes used to accelerate protein hydrolysis, making food more digestable. In such a treatment chloride is thought to react with the glycerol backbone of lipids to produce 2- and 3-MCPD.
Further reading
Kuhlmann, Jan (2019). "2-Monochloropropanediol (2-MCPD), 3-Monochloropropanediol (3-MCPD), and Glycidol in Infant and Adult/Pediatric Nutritional Formula: Single-Laboratory Validation, First Action 2018.12". Journal of AOAC International. 102 (4): 1205–1220. doi:10.5740/jaoacint.19-0026. PMID 30992094.
Buhrke, T.; Frenzel, F.; Kuhlmann, J.; Lampen, A. (2015). "2-Chloro-1,3-propanediol (2-MCPD) and its fatty acid esters: Cytotoxicity, metabolism, and transport by human intestinal Caco-2 cells". Archives of Toxicology. 89 (12): 2243–2251. doi:10.1007/s00204-014-1395-3. PMID 25354796.
References
External links
Media related to 3-Chloro-1,2-propandiol at Wikimedia Commons
Chloropropanols (WHO Food Additive Series 32)
Kata Kunci Pencarian:
- Farmakodinamika
- Kontaminan pengolahan makanan
- Peristiwa Toko Roti Esing
- 2-MCPD
- 3-MCPD
- Margarine
- Palm oil
- Hydrolyzed vegetable protein
- C3H7ClO2
- Montgomery County Police Department
- 1,3-Dichloropropan-2-ol
- Oyster sauce
- Pharmacodynamics
