- Source: 2000 Toronto Argonauts season
The 2000 Toronto Argonauts finished in fourth place in the East Division of the 2000 CFL season with a 7–10–1 record and failed to qualify for the playoffs.
Offseason
= CFL draft
== Preseason
=† The CFL had scheduled a demonstration of the league's new overtime format following the game regardless of whether the score necessitated it.
Regular season
= Season standings
== Schedule
=Postseason
Despite a late season run (6–4–0) under interim coach Michael "Pinball" Clemons, the Argonauts failed to qualify for the playoffs.
Awards and records
= 2000 CFL All-Stars
=SB – Derrell Mitchell
P – Noel Prefontaine
= Eastern Division All-Star Selections
=SB – Derrell Mitchell
DT – Johnny Scott
LB – Mike O'Shea
LB – Calvin Tiggle
P – Noel Prefontaine