• Source: 3-hydroxybutyryl-CoA dehydratase

The enzyme 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) catalyzes the chemical reaction

(3R)-3-hydroxybutanoyl-CoA



⇌


{\displaystyle \rightleftharpoons }

crotonoyl-CoA + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming). Other names in common use include D-3-hydroxybutyryl coenzyme A dehydratase, D-3-hydroxybutyryl-CoA dehydratase, enoyl coenzyme A hydrase (D), and (3R)-3-hydroxybutanoyl-CoA hydro-lyase. This enzyme participates in butanoate metabolism.




References



Moskowitz GJ, Merrick JM (1969). "Metabolism of poly-beta-hydroxybutyrate. II. Enzymatic synthesis of D-(−)-beta hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum". Biochemistry. 8 (7): 2748–55. doi:10.1021/bi00835a009. PMID 5808333.

Kata Kunci Pencarian:

• 3-hydroxybutyryl-CoA dehydratase
• 3-Hydroxybutyryl-CoA dehydrogenase
• 4-hydroxybutanoyl-CoA dehydratase
• Butyrate fermentation
• Enoyl coenzyme A hydrase (D)
• Butyric acid
• List of EC numbers (EC 4)
• Α-Ketobutyric acid
• Threonine
• Valine