- Source: 3-oxoacyl-(acyl-carrier-protein) reductase (NADH)
In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) (EC 1.1.1.212) is an enzyme that catalyzes the chemical reaction
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD+
⇌
{\displaystyle \rightleftharpoons }
3-oxoacyl-[acyl-carrier-protein] + NADH + H+
Thus, the two substrates of this enzyme are [[(3R)-3-hydroxyacyl-[acyl-carrier-protein]]] and NAD+, whereas its 3 products are [[3-oxoacyl-[acyl-carrier-protein]]], NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).
References
Caughey I, Kekwick RG (1982). "The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit". Eur. J. Biochem. 123 (3): 553–61. doi:10.1111/j.1432-1033.1982.tb06568.x. PMID 7075600.
Kata Kunci Pencarian:
- 3-oxoacyl-(acyl-carrier-protein) reductase (NADH)
- Fatty-acyl-CoA synthase
- Index of molecular biology articles
- Mupirocin
- List of EC numbers (EC 1)
- List of EC numbers (EC 2)
- HSD17B8
- List of MeSH codes (D08)
