- Source: 3beta(or 20alpha)-hydroxysteroid dehydrogenase
In enzymology, a 3-β(or 20-α)-hydroxysteroid dehydrogenase (EC 1.1.1.210) is an enzyme that catalyzes the chemical reaction
5α-androstan-3β,17β-diol + NADP+
⇌
{\displaystyle \rightleftharpoons }
17β-hydroxy-5α-androstan-3-one + NADPH + H+
This enzyme possesses the combined activities of the 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase and 20-α-hydroxysteroid dehydrogenase enzymes.
