- Source: 5F-APINACA
5F-APINACA (also known as A-5F-PINACA, 5F-AKB-48 or 5F-AKB48) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as an example, it is very similar to the corresponding pentanenitrile and 4-chlorobutyl compounds which are claimed as examples 3 and 4.
5F-APINACA was first identified in South Korea. It is expected to be a potent agonist of the CB1 receptor and CB2 receptor. Its metabolism has been described in literature.
Pharmacology
5F-APINACA acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.
Legality
In the United States, 5F-APINACA is a Schedule I controlled substance.
5F-APINACA is an Anlage II controlled drug in Germany since July 2013.
As of October 2015, 5F-APINACA is a controlled substance in China.
5F-APINACA is banned in the Czech Republic.
See also
References
External links
Abouchedid R, Ho JH, Hudson S, Dines A, Archer JR, Wood DM, et al. (December 2016). "Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation". Journal of Medical Toxicology. 12 (4): 396–401. doi:10.1007/s13181-016-0571-7. PMC 5135680. PMID 27456262.
Kata Kunci Pencarian:
- 5F-APINACA
- 5F-ADB
- APINACA
- 5F-AMB
- ADB-BUTINACA
- List of Schedule I controlled substances (U.S.)
- Synthetic cannabinoids
- Conversion of CBD to THC
- Hyoscyamus niger
- List of designer drugs
