- Source: Acetylenecarboxylate hydratase
The enzyme acetylenecarboxylate hydratase (EC 4.2.1.27) catalyzes the chemical reaction
3-oxopropanoate
⇌
{\displaystyle \rightleftharpoons }
propynoate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-oxopropanoate hydro-lyase (propynoate-forming). Other names in common use include acetylenemonocarboxylate hydratase, alkynoate hydratase, acetylenemonocarboxylate hydrase, acetylenemonocarboxylic acid hydrase, malonate-semialdehyde dehydratase, and 3-oxopropanoate hydro-lyase. This enzyme participates in 3 metabolic pathways: beta-alanine metabolism, propanoate metabolism, and butanoate metabolism.
References
Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953.
YAMADA EW, JAKOBY WB (1959). "Enzymatic utilization of acetylenic compounds. II Acetylenemonocarboxylic acid hydrase". J. Biol. Chem. 234 (4): 941–5. PMID 13654296.
