- Source: Acetylesterase
In biochemistry, an acetylesterase (EC 3.1.1.6) is a class of enzyme which catalyzes the hydrolysis of acetic esters into an alcohol and acetic acid:
R
−
OC
(
O
)
CH
3
+
H
2
O
→
acetylesterase
R
−
OH
+
HO
−
C
(
O
)
CH
3
{\displaystyle {\ce {R-OC(O)CH3 + H2O}}\quad {\xrightarrow[{\text{acetylesterase}}]{}}\quad {\ce {R-OH + HO-C(O)CH3}}}
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds (esterases). The systematic name of this enzyme class is acetic-ester acetylhydrolase. Other names in common use include C-esterase (in animal tissues), acetic ester hydrolase, chloroesterase, p-nitrophenyl acetate esterase, and citrus acetylesterase.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1BS9, 1G66, and 2AXE.
References
Aldridge WN (January 1953). "Serum esterases. I. Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate, and a method for their determination". The Biochemical Journal. 53 (1): 110–7. doi:10.1042/bj0530110. PMC 1198110. PMID 13032041.
Bergmann F, Rimon S (November 1960). "Fractionation of C-esterase from the hog's kidney extract" (PDF). The Biochemical Journal. 77 (2): 209–14. doi:10.1042/bj0770209. PMC 1204974. PMID 16748846.
Jansen EF, Nutting MD, Balls AK (September 1948). "The reversible inhibition of acetylesterase by diisopropyl fluorophosphate and tetraethyl pyrophosphate" (PDF). The Journal of Biological Chemistry. 175 (2): 975–87. doi:10.1016/S0021-9258(18)57217-3. PMID 18880795.
Kata Kunci Pencarian:
- Acetylesterase
- Rhamnogalacturonan acetylesterase
- Sialate O-acetylesterase
- Cigarette
- Esterase
- Acetylajmaline esterase
- Serine hydrolase
- Cephalosporin-C deacetylase
- List of EC numbers (EC 3)
- Hemagglutinin esterase
