• Source: ACOT8

Acyl-coenzyme A thioesterase 8 is an enzyme that in humans is encoded by the ACOT8 gene.
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene.




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External links


ACOT8 human gene location in the UCSC Genome Browser.
ACOT8 human gene details in the UCSC Genome Browser.

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/1
• ACOT8
• List of human protein-coding genes 1
• Thioesterase
• Melanin-concentrating hormone receptor 2