- Source: Adenosylcobinamide-GDP ribazoletransferase
Adenosylcobinamide-GDP ribazoletransferase (EC 2.7.8.26, CobS, cobalamin synthase, cobalamin-5'-phosphate synthase, cobalamin (5'-phosphate) synthase) is an enzyme with systematic name adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase. This enzyme catalyses the following chemical reaction
(1) adenosylcobinamide-GDP + alpha-ribazole
⇌
{\displaystyle \rightleftharpoons }
GMP + adenosylcobalamin
(2) adenosylcobinamide-GDP + alpha-ribazole 5'-phosphate
⇌
{\displaystyle \rightleftharpoons }
GMP + adenosylcobalamin 5'-phosphate
This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria.
See also
Cobalamin biosynthesis
References
External links
Adenosylcobinamide-GDP+ribazoletransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)