• Source: AGH-107

AGH-107 is a potent, selective, water-soluble and brain penetrant full agonist at the 5HT7 serotonin receptor. AGH-107 is one of the few examples of low-basicity aminergic receptor agonists, which may underlie its high selectivity over the related central nervous system targets. AGH-107 was found to reverse the impairment in novel object recognition caused by MK-801 in mice. The relatively short half-life in rodents inhibited its use as a molecular probe.




See also


AH-494
AGH-192




References

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• AGH-107
• AGH-192
• AH-494
• 5-HT7 receptor
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• Swiss Federal Laboratories for Materials Science and Technology