- Source: AGPAT9
Glycerol-3-phosphate acyltransferase 3 (GPAT-3) is an enzyme that in humans is encoded by the AGPAT9 gene. GPAT-3 is also known as:
1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9),
lysophosphatidic acid acyltransferase theta (LPAAT-theta), or
lung cancer metastasis-associated protein 1.
Function
Glycerol-3-phosphate (G3P) acyltransferases (GPAT; EC 2.3.1.15), such as GPAM and GPAT3 (this enzyme), catalyze the initial step of de novo triacylglycerol (TAG) synthesis by converting glycerol-3-phosphate (G3P) to lysophosphatidic acid (LPA).
References
External links
Human GPAT3 genome location and GPAT3 gene details page in the UCSC Genome Browser.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
