• Source: AKAP8

A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene.




Function


The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining it to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is redistributed to distinct locations during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.




Interactions


AKAP8 has been demonstrated to interact with:

Cyclin D3
DDX5,
MCM2,
MYCBP, and
PRKAR2A.




References






Further reading






External links


AKAP8 human gene location in the UCSC Genome Browser.
AKAP8 human gene details in the UCSC Genome Browser.

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/1
• AKAP8
• List of human protein-coding genes 1
• List of human transcription factors
• A-kinase-anchoring protein
• Stress granule
• DDX5
• MCM2
• PRKAR2A
• Cyclin D3