• Source: Anisocytosis

Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is commonly found in anemia and other blood conditions. False diagnostic flagging may be triggered on a complete blood count by an elevated WBC count, agglutinated RBCs, RBC fragments, giant platelets or platelet clumps due to anisocytosis. In addition, it is a characteristic feature of bovine blood.
The red cell distribution width (RDW) is a measurement of anisocytosis and is calculated as a coefficient of variation of the distribution of RBC volumes divided by the mean corpuscular volume (MCV).




Types


Anisocytosis is identified by RDW and is classified according to the size of RBC measured by MCV. According to this, it can be divided into

Anisocytosis with microcytosis – Iron deficiency, sickle cell anemia
Anisocytosis with macrocytosis – Folate or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome
Increased RDW is seen in iron deficiency anemia and decreased or normal in thalassemia major (Cooley's anemia), thalassemia intermedia

Anisocytosis with normal RBC size – Early iron, vit B12 or folate deficiency, dimorphic anemia, Sickle cell disease, chronic liver disease, myelodysplastic syndrome




Etymology


From Ancient Greek: an- without, or negative quality, iso- equal, cyt- cell, -osis condition.




See also


Anisopoikilocytosis
Poikilocytosis
Red blood cell distribution width




References






External links

Kata Kunci Pencarian:

• Anisocytosis
• Red blood cell distribution width
• Anisopoikilocytosis
• Poikilocytosis
• Microcytic anemia
• Cytosis
• Megaloblastic anemia
• Complete blood count
• Macrocytic anemia
• List of medical roots, suffixes and prefixes