- Source: Apolipoprotein A-II
Apolipoprotein A-II is a protein that in humans is encoded by the APOA2 gene. It is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. Remarkably, defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
Interactions
ApoA-II has been shown to interact with phospholipid transfer protein.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
References
External links
Human APOA2 genome location and APOA2 gene details page in the UCSC Genome Browser.
Further reading
Kata Kunci Pencarian:
- Hiperkolesterolemia familia
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- Apolipoprotein A-II
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