- Source: Baccatin III
Baccatin III is an isolate from the yew tree (Genera Taxus). Baccatin III is a precursor to the anti-cancer drug paclitaxel (Taxol).
In 2014, researchers reported introduction and expression of the endophytic fungal gene responsible for synthesizing baccatin III (10-deacetylbaccatin III 10-O-acetyltransferase), to the mushroom Flammulina velutipes. Researchers achieved the same accomplishment with Escherichia coli in 2000.
See also
10-Deacetylbaccatin
Taxadiene
References
Kata Kunci Pencarian:
- Baccatin III
- 10-Deacetylbaccatin
- Paclitaxel
- Taxadiene
- Organic synthesis
- 10-deacetylbaccatin III 10-O-acetyltransferase
- Paclitaxel total synthesis
- Vinyl iodide functional group
- Takahashi Taxol total synthesis
- Johnson–Corey–Chaykovsky reaction