• Source: Calpain-1 catalytic subunit

Calpain-1 catalytic subunit (CANP 1) is a protein that in humans is encoded by the CAPN1 gene.




Function


The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1.




Interactions


CAPN1 has been shown to interact with PSEN2.




References






Further reading






External links


The MEROPS online database for peptidases and their inhibitors: C02.001 Archived 2008-01-15 at the Wayback Machine
Human CAPN1 genome location and CAPN1 gene details page in the UCSC Genome Browser.

Kata Kunci Pencarian:

• Calpain-1 catalytic subunit
• Calpain-2 catalytic subunit
• Calpain-6
• Calpain-9
• Calpain-2
• CAPN10
• POLD1
• Protein kinase C
• Housekeeping gene
• Catalytic triad