- Source: Calu-3
- Serigala
- Aji Muhammad Sulaiman
- Keboansikep, Gedangan, Sidoarjo
- Daftar gen penyandi protein pada manusia/1
- Nama Portugis
- Daftar karakter Aikatsu Friends!
- Daftar pembawa acara televisi
- Daftar tokoh yang meninggal akibat pandemi Covid-19
- Calu-3
- Cell culture
- Itaconic acid
- Calumenin
- Aita
- Călușari
- Chalus River
- COVID-19 drug repurposing research
- Camostat
- Carlos Lima
3/info/calu" target="_blank">Calu-3 is a human lung cancer cell line commonly used in cancer research and drug development. 3/info/calu" target="_blank">Calu-3 cells are epithelial and can act as respiratory models in preclinical applications.
3/info/calu" target="_blank">Calu-3 cells were first derived in 1975 by Germain Trempe and Jorgen Fogh of the Memorial Sloan Kettering Cancer Center. The cells were isolated from the pleural effusion of a 25-year-old Caucasian male with a lung adenocarcinoma.
The 3/info/calu" target="_blank">Calu-3 cell line grows as an adherent monolayer and overexpresses the ERBB2 gene, leading to active ErbB2/Her2. The cells also express CK7, occludin, and E-cadherin. 3/info/calu" target="_blank">Calu-3 cells also have large amounts of cystic fibrosis transmembrane conductance regulator.
3/info/calu" target="_blank">Calu-3 cells are commonly used as both in vitro and in vivo models for drug development against lung cancer. The cells have been used in studies of pulmonary drug delivery, demonstrating a capacity to intake low molecular weight substances. 3/info/calu" target="_blank">Calu-3 cells have served as respiratory models for air intake and lung injury due to their responsiveness to foreign substances. The 3/info/calu" target="_blank">Calu-3 cell line has shown to be useful in the study of chloride ion secretion by lung epithelial cells. The cells may be used in high-throughput screening applications focused on barrier integrity and surface protein expression of lung cells.
External links
Cellosaurus entry for 3/info/calu" target="_blank">Calu-3