- Source: Cardiac stimulant
A cardiac stimulant is a drug which acts as a stimulant of the heart – e.g., via positive chronotropic action (increased heart rate) and/or inotropic action (increased myocardial contractility). They increase cardiac output (the amount of blood pumped by the heart over time).
Examples
β1-Adrenergic receptor agonists like epinephrine, norepinephrine, dopamine, dobutamine, denopamine, isoproterenol, and xamoterol
Adrenergic agents indirectly activating β1-adrenergic receptors
Norepinephrine prodrugs like droxidopa
Norepinephrine reuptake inhibitors like atomoxetine, reboxetine, desipramine, nortriptyline, bupropion, milnacipran, methylphenidate, and cocaine
Norepinephrine releasing agents like amphetamine, methamphetamine, ephedrine, pseudoephedrine, phenylpropanolamine, and mephentermine
α1-Adrenergic receptor antagonists like phentolamine, prazosin, terazosin, and doxazosin
α2-Adrenergic receptor antagonists like phentolamine, yohimbine, and atipamezole
Antimuscarinic anticholinergics like atropine
Adenosine receptor antagonists like caffeine, theophylline, and aminophylline
PDE3 inhibitors like amrinone, milrinone, and pimobendan
Cardiac glycosides like digoxin
Other agents like hydralazine, levosimendan, and cannabinoids
Exercise is also a cardiac stimulant by increasing levels of the sympathomimetic catecholamines epinephrine and norepinephrine.
References
External links
Media related to Cardiac stimulants at Wikimedia Commons
Kata Kunci Pencarian:
- Efedrin
- Cardiac stimulant
- Arbutamine
- Stimulant
- Methamphetamine
- Ephedrine
- Cocaine
- Alkanolamine
- ATC code C01
- Proxyphylline
- Mephentermine