• Source: CD120

CD120 (Cluster of Differentiation 120) can refer to two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2).




Receptor subtypes


There are two variants of the receptor, each encoded by a separate gene:

CD120a - TNFR1 - TNFR superfamily member 1A
CD120b - TNFR2 - TNFR superfamily member 1B
TNFR1 is the receptor type responsible for mediation of TNF-alpha induced sickness behavior, and is involved in neurotoxic processes. Elevated levels of TNFR1 has been found in severe mental disorders.




Signaling pathway






See also


Cluster of differentiation




References






External links


CD120a+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
CD120b+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• CD120
• List of minor planets: 86001–87000
• Kell antigen system
• List of minor planets: 667001–668000
• CD4
• PD-L1
• Major prion protein
• List of minor planets: 251001–252000
• Programmed cell death protein 1
• List of minor planets: 200001–201000