• Source: CDC16

Cell division cycle protein 16 homolog is a protein that in humans is encoded by the CDC16 gene.




Function


This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified.




Interactions


CDC16 has been shown to interact with CDC27 and CDC20.




References






External links


Human CDC16 genome location and CDC16 gene details page in the UCSC Genome Browser.




Further reading

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/1
• CDC16
• Anaphase-promoting complex
• TBC
• TBC domain
• Tetratricopeptide repeat
• List of human protein-coding genes 1
• Marc Kirschner
• TBC1D12
• TBC1D1
• PRP36