• Source: CEBPE

CCAAT/enhancer binding protein (C/EBP), epsilon, also known as CEBPE and CRP1, is a type of ccaat-enhancer-binding protein. CEBPE is its human gene and is pro-apoptotic.
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-δ. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with specific granule deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.




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External links


CEBPE protein, human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human CEBPE genome location and CEBPE gene details page in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Kata Kunci Pencarian:

• Resistin
• Daftar gen penyandi protein pada manusia/1
• CEBPE
• Specific granule
• List of human transcription factors
• List of human protein-coding genes 1
• CIROP gene
• Acute lymphoblastic leukemia
• Neutrophil-specific granule deficiency
• BZIP domain
• RELA
• C8orf48