- Source: Centric heterochromatin
Centric heterochromatin, a variety of heterochromatin, is a tightly packed form of DNA. Centric heterochromatin is a constituent in the formation of active centromeres in most higher-order organisms; the domain exists on both mitotic and interphase chromosomes.
Centric heterochromatin is usually formed on alpha satellite DNA in humans; however, there have been cases where centric heterochromatin and centromeres have formed on originally euchromatin domains lacking alpha satellite DNA; this usually happens as a result of a chromosome breakage event and the formed centromere is called a neocentromere.
Centric heterochromatin domains are flanked by pericentric heterochromatin.
See also
Heterochromatin
References
Kata Kunci Pencarian:
- Centric heterochromatin
- Heterochromatin
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- 60S ribosomal protein L38
- RNA-induced silencing complex
- X-inactivation
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