- Source: Citrullinase
In enzymology, a citrullinase (EC 3.5.1.20) is an enzyme that catalyzes the chemical reaction
L-citrulline + H2O
⇌
{\displaystyle \rightleftharpoons }
L-ornithine + CO2 + NH3
Thus, the two substrates of this enzyme are L-citrulline and H2O, whereas its 3 products are L-ornithine, CO2, and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is L-citrulline N5-carbamoyldihydrolase. Other names in common use include citrulline ureidase, citrulline hydrolase, and L-citrulline 5-N-carbamoyldihydrolase.
References
Hill DL, Chambers P (1967). "The biosynthesis of proline by Tetrahymena pyriformis". Biochim. Biophys. Acta. 148 (2): 435–47. doi:10.1016/0304-4165(67)90140-7. PMID 6075416.
