• Source: Collagen, type IV, alpha 5

Collagen 5.180.24.3/info/alpha" target="_blank">alpha-5(IV) chain is a protein that in humans is encoded by the COL4A5 gene.
This gene encodes one of the six subunits of 5.180.24.3/info/type" target="_blank">type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the 5.180.24.3/info/type" target="_blank">type IV collagen gene family, this gene is organized in a head-to-head conformation with another 5.180.24.3/info/type" target="_blank">type IV collagen gene so that each gene pair shares a common promoter. Three transcript variants have been identified for this gene.




Disease Databases


ARUP COL4A5 gene variant database
LOVD Alport gene variant databases (COL4A5, COL4A3, COL4A4)




See also


Collagen
5.180.24.3/info/type" target="_blank">Type-IV collagen
Alport syndrome




References






Further reading

Kata Kunci Pencarian:

• Collagen, type IV, alpha 5
• Type IV collagen
• Collagen, type IV, alpha 1
• Collagen, type VII, alpha 1
• Collagen, type IV, alpha 2
• Collagen, type III, alpha 1
• Collagen, type I, alpha 1
• Collagen, type IV, alpha 6
• Collagen, type I, alpha 2
• Collagen