• Source: Core binding factor

The Core binding factor (CBF) is a group of heterodimeric transcription factors.
Core binding factors are composed of:

a non-DNA-binding CBFβ chain (CBFB)
a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)




References


de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function". Oncogene. 23 (24): 4238–48. doi:10.1038/sj.onc.1207763. PMID 15156179.




See also


AI-10-49, an anti-leukemic drug under development.




External links


Core+Binding+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• CREB3
• Leukemia mieloid akut
• Vitamin D
• Besi
• Nikel
• Proteasom
• Core binding factor
• RUNX1
• CAAT box
• Nerve growth factor
• CBFB
• AI-10-49
• RUNX2
• Transcription factor
• CBF
• Nucleolus