• Source: CRMP1

Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory.
CRMP1 gene overlaps with another gene called EVC.




Interactions


CRMP1 has been shown to interact with DPYSL2.




References






External links


Human CRMP1 genome location and CRMP1 gene details page in the UCSC Genome Browser.




Further reading

Kata Kunci Pencarian:

• DPYSL2
• Daftar gen penyandi protein pada manusia/1
• CRMP1
• List of human protein-coding genes 1
• Chromosome 4
• Neuronal lineage marker
• Collapsin response mediator protein family
• EVC (gene)
• DPYSL2
• Cyclin-dependent kinase 5
• Chromosome 4 open reading frame 50
• NDUFV2