• Source: Dermatopathic lymphadenopathy
  • In pathology, dermatopathic lymphadenopathy, is lymph node pathology due to skin disease.


    Cause


    Also known as lipomelanotic reticulosis or Pautrier-Woringer disease, represents a rare form of benign lymphatic hyperplasia associated with most exfoliative or eczematoid inflammatory erythrodermas, including pemphigus, psoriasis, eczema, neurodermatitis, and atrophia senilis.


    Diagnosis


    Dermatopathic lymphadenopathy is diagnosed by a lymph node biopsy. It has a characteristic pattern of histomorphology and immunohistochemical staining:

    Paracortical histiocytosis
    Melanin-laden macrophages
    Eosinophils
    Plasma cells (medulla of lymph node)


    = Differential diagnosis

    =
    Cutaneous T cell lymphoma
    Hodgkin's lymphoma
    Melanoma


    Treatment


    The treatment is based on the underlying cause.


    See also


    Skin disease
    List of cutaneous conditions


    References




    External links


    Dermatopathic lymphadenitis - pathconsultddx.com.

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