• Source: DLX1

Homeobox protein DLX-1 is a protein that in humans is encoded by the DLX1 gene.




Function


This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-β superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.




References






Further reading

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/1
• DLX1
• Rat
• Ectrodactyly
• DLX gene family
• Homeobox
• List of human transcription factors
• List of human protein-coding genes 1
• Ganglionic eminence
• Syndromic microphthalmia
• AAZ-A-154