- Source: DPH-362
DPH-362 is a simplified amitriptyline analog created by omission of the two-carbon dibenzosuberane bridge (the seven membered ring). The resulting compound still had activity in a test to explore TCA sodium channel blockers with analgesic properties.
It is based on previous structures such as Spasmolytic A29 (one of the active ingredients in Ketogan) and SKF-89976A.
See also
Amitriptyline
γ-Butyrolactone