- Source: DTDP-galactose 6-dehydrogenase
In enzymology, a dTDP-galactose 6-dehydrogenase (EC 1.1.1.186) is an enzyme that catalyzes the chemical reaction
dTDP-D-galactose + 2 NADP+ + H2O
⇌
{\displaystyle \rightleftharpoons }
dTDP-D-galacturonate + 2 NADPH + 2 H+
The 3 substrates of this enzyme are dTDP-D-galactose, NADP+, and H2O, whereas its 3 products are dTDP-D-galacturonate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dTDP-D-galactose:NADP+ 6-oxidoreductase. This enzyme is also called thymidine-diphosphate-galactose dehydrogenase. This enzyme participates in nucleotide sugars metabolism.
References
Katan R, Avigad G (1966). "NADP dependent oxidation of TDP-glucose by an enzyme system from sugar beets". Biochem. Biophys. Res. Commun. 24 (1): 18–24. doi:10.1016/0006-291X(66)90403-7. PMID 4381717.
Kata Kunci Pencarian:
- DTDP-galactose 6-dehydrogenase
- List of EC numbers (EC 1)
- List of EC numbers (EC 2)
- List of EC numbers (EC 5)
