• Source: Exosome component 2
    • Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene.


      Function


      Mammalian mRNAs contain AU-rich elements (AREs) within their three prime untranslated regions. In yeast, 3-prime-to-5-prime mRNA degradation is mediated by the exosome, a multisubunit particle. EXOSC2 (which is homologous to the yeast Rrp4 protein) is a component of the human exosome.


      Interactions


      Exosome component 2 has been shown to interact with:

      Exosome component 4, and
      Exosome component 7.


      References




      Further reading

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