- Source: Fatty acid oxidation inhibitors
Fatty acid oxidation inhibitors are a new potent class of drugs used in treatment of stable angina pectoris and an addition in treatment of chronic heart failure.
Drugs
CPT-I inhibitors: etomoxir, oxfenicine, perhexiline CPT-I (carnitine palmitoyl transferase) converts fatty acyl-CoA to fatty acyl-carnitine.
Carnitine biosynthesis inhibitor: mildronate
3-KAT inhibitors: trimetazidine 3-KAT (3-ketoacyl-coenzyme A thiolase) inhibitors directly inhibits fatty acid beta-oxidation.
pFOX directly inhibits fatty acid beta-oxidation.
References
Kata Kunci Pencarian:
- Efedrin
- Fosforilasi oksidatif
- Fatty acid oxidation inhibitors
- Fatty acid metabolism
- Randle cycle
- Linoleic acid
- Trimetazidine
- Arachidonic acid
- Fatty acid synthesis
- Citric acid cycle
- Lipid metabolism
- Α-Linolenic acid
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